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Tos-PEG2-CH2-Boc
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tos-PEG2-CH2-Boc图片
CAS NO: 882518-89-0
包装与价格:
包装 价格(元)
100mg 电议
250mg 电议
1g 电议

半岛bd体育手机客户端 介绍
Tos-PEG2-CH2-Boc 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。
Cas No. 882518-89-0
分子式 C17H26O7S
分子量 374.45
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

Tos-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

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