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Biotin-PEG-azide(MW 600)
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Biotin-PEG-azide(MW 600)图片
CAS NO: 956494-20-5
包装与价格:
包装 价格(元)
100mg 电议
250mg 电议
500mg 电议

半岛bd体育手机客户端 介绍
Biotin-PEG-azide (MW 600) 是基于 PEG 结构的 PROTAC linker,可以用来制备 PROTAC。
Cas No. 956494-20-5
分子量 600.00(Average)
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

Biotin-PEG-azide (MW 600) is a PEG-basedPROTAC linkercan be used in the synthesis of PROTAC[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein[1].
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

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