| CAS： |
1628287-16-0 |
| 分子式： |
C23H20ClF3N4O5 |
| 分子量： |
524.88 |
| 纯度： |
>98% |
| 溶解性： |
DMSO : ≥ 100 mg/mL (190.52 mM) |
| 存储： |
Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
| 研究领域： |
Cancer |
| Target： |
IC50: 0.349 nM (TRPC4, cell assay), 1.3 nM (TRPC5, cell assay), 0.03 nM (TRPC4-TRPC1, cell assay), 0.2 nM (TRPC5-TRPC1, cell assay) |
| 描述： |
Pico145 is a remarkable inhibitor of TRPC1/4/5 channels, inhibits (?)-englerin A-activated TRPC4/TRPC5 channels, with IC50s of 0.349 and 1.3 nM in cells, and shows no effect on TRPC3, TRPC6, TRPV1, TR |
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