| CAS： |
229005-80-5 |
| 分子式： |
C33H39ClN2O2 |
| 分子量： |
531.13 |
| 纯度： |
≥98% |
| 溶解性： |
DMSO |
| 存储： |
Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
| 研究领域： |
Infection/Inflammation/Immunology |
| Target： |
Ki: 1.1 nM (CCR5)[1]EC50: 1.2 nM (R5 HIV-1, in MAGI-CCR5 cells)[1]EC90: 5.7 nM (R5 HIV-1, in MAGI-CCR5 cells)[1]CXCR[2] |
| 描述： |
TAK-779 is a potent and selective nonpeptide antagonist of CCR5 and CXCR3, with a Ki of 1.1 nM for CCR5, and effectively and selectively inhibits R5 HIV-1, with EC50 and EC90 of 1.2 nM and 5.7 nM, res |
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