分子式: |
C25H19N5NaS |
分子量: |
444.51 |
纯度: |
>98% |
溶解性: |
DMSO |
存储: |
Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months; -20℃ 1 month |
研究领域: |
Cancer |
Target: |
IC50: 12 nM (ALK5, cell-based), 45 nM (ALK4 cell-based), 7.5 nM (ALK7 cell-based)[1] |
描述: |
A 83-01 sodium salt is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7, with IC50s of 12, 45 and 7.5 nM against the transcrip |