| CAS： |
909910-43-6 |
| 分子式： |
C25H19N5S |
| 分子量： |
421.52 |
| 纯度： |
≥98% |
| 溶解性： |
DMSO |
| 存储： |
Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
| 研究领域： |
Cancer |
| Target： |
IC50: 12 nM (ALK5, cell-based), 45 nM (ALK4 cell-based), 7.5 nM (ALK7 cell-based)[1] |
| 描述： |
A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7, with IC50 of 12, 45 and 7.5 nM against the transcription induced |
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