| 半岛bd体育手机客户端 名称： |
司马西特 |
| CAS： |
425386-60-3 |
| 分子式： |
C19H27N3O4 |
| 分子量： |
361.44 |
| 纯度： |
>98% |
| 溶解性： |
DMSO |
| 存储： |
Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
| 研究领域： |
Neurological Disease |
| Target： |
IC50: 10.9 nM (Aβ42), 12 nM (Aβ38), 12.1 nM (Aβ40), 14.1 nM (Notch) |
| 描述： |
Semagacestat is a γ-secretase inhibitor, inhibits β-amyloid (Aβ42), Aβ38 and Aβ40 with IC50 of 10.9, 12 and 12.1 nM, respectively; also inhibits Notch signaling with IC50 of 14.1 nM. |
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