| CAS： |
2101314-20-7 |
| 分子式： |
C27H28ClN7O2S |
| 分子量： |
550.07 |
| 纯度： |
≥98% |
| 溶解性： |
DMSO |
| 存储： |
Powder -20℃ 3 years; 4℃ 2 years In solvent -80℃ 6 months;-20℃ 1 month |
| 研究领域： |
Cancer |
| Target： |
IC50: 54 nM (rRNA synthesis, MIA PaCa-2 cells), 113 nM (rRNA synthesis, A375 cells), 142 nM (rRNA synthesis, HCT-116 cells)[1] |
| 描述： |
CX-5416 HCl is a potent and orally bioavailable inhibitor of Pol I-mediated rRNA synthesis, with IC50 of 142 nM in HCT-116, 113 nM in A375, and 54 nM in MIA PaCa-2 cells, and shows little or no effect |
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