| CAS NO: | 1204329-34-9 |
| 包装: | 5mg |
| 市场价: | 1890元 |
| Cas No. | 1204329-34-9 |
| Canonical SMILES | NC(NC(C1=CC=C(C2CCN(C(C)=O)CC2)C(C(F)(F)F)=C1)=O)=N |
| 分子式 | C16H19F3N4O2 |
| 分子量 | 356.34 |
| 溶解度 | DMF: 10mg/mL,DMSO: 20mg/mL,DMSO:PBS (pH 7.2) (1:7): 0.12mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 | BI-9627 is a sodium-hydrogen exchanger isoform 1 (NHE1) inhibitor with an EC50 of 31 nM[1]. EC50: 31 nM (Sodium-hydrogen exchanger isoform 1)[1] [1]. Huber JD, et al. Identification of a potent sodium hydrogen exchanger isoform 1 (NHE1) inhibitor with a suitableprofile for chronic dosing and demonstrated cardioprotective effects in a preclinical model of myocardial infarction in the rat. J Med Chem. 2012 Aug 23;55(16):7114-40. |
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