PD 161570 是一种有效的 ATP 竞争性人 FGF-1 受体抑制剂,IC50 为 39.9 nM,Ki 为 42 nM。
Cas No. |
192705-80-9 |
化学名 |
(r)-1-(tert-butyl)-3-(6-(2,6-dichlorophenyl)-2-((4-(diethylamino)butyl)amino)pyrido[2,3-d]pyrimidin-7-yl)urea |
Canonical SMILES |
ClC1=[C@@](C(Cl)=CC=C1)[C@@]2=CC3=CN=C(N=C3N=C2NC(NC(C)(C)C)=O)NCCCCN(CC)CC |
分子式 |
C26H35Cl2N7O |
分子量 |
532.51 |
溶解度 |
<53.25mg/ml in DMSO;<53.25mg/ml in ethanol |
储存条件 |
Store at RT |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |