Taurodeoxychloic Acid sodium hydrate - 半岛电竞官方网址

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Taurodeoxychloic Acid sodium hydrate

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

110026-03-4

包装与价格：

半岛bd体育手机客户端介绍

Taurodeoxychloic Acid sodium hydrate (Sodium taurodeoxycholate monohydrate) 是一种胆汁酸，是一种由肝脏中的胆固醇合成的两亲表面活性剂分子。

Cas No.	110026-03-4
别名	牛磺猪去氧胆酸,Sodium taurodeoxycholate monohydrate
Canonical SMILES	C[C@H](CCC(NCCS(=O)(O)=O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C.[Na+].O
分子式	C₂₆H₄₇NNaO₇S+
分子量	540.71
溶解度	DMSO: 125 mg/mL (231.61 mM)
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	Taurodeoxychloic Acid (sodium hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxychloic Acid (sodium hydrate) is investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis[1]. Caspase-12 Taurodeoxychloic Acid (TUDCA) is neuroprotective in a transgenic animal model of Huntington's disease[2]. [1]. Xie Q, et al. Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology. 2002 Sep;36(3):592-601. [2]. Keene CD, et al. Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10671-6.