棕榈酰左旋肉碱(氯化物)是一种长链酰基肉碱和脂肪酸代谢物,在缺血期间积聚在肌膜中并破坏膜脂环境。
Cas No. | 18877-64-0 |
别名 | L-氯化棕榈酰肉碱 |
Canonical SMILES | OC(C[C@H](C[N+](C)(C)C)OC(CCCCCCCCCCCCCCC)=O)=O.[Cl-] |
分子式 | C23H46NO4•Cl |
分子量 | 436.1 |
溶解度 | Water: slightly, heated, sonicated |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
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描述 | Palmitoyl-L-carnitine is a naturally occurring long-chain acylcarnitine and the L-enantiomer of palmitoyl-DL-carnitine . In cells, palmitoyl-L-carnitine is transported into mitochondria via carnitine palmitoyl transferase II to deliver palmitate for fatty acid oxidation and energy production. It also inhibits lecithin:cholesterol acyltransferase activity in rat, but not human, plasma when used at a concentration of 500 µM. In vivo, palmitoyl-L-carnitine increases intestinal absorption of the antibiotic cefoxitin in rat intestine. |