您好，欢迎来到半岛电竞官方网址 ！ [ 登录] [ 免费注册]
半岛电竞官方网址
发布求购
位置： 首页> 半岛bd体育手机客户端 库> 2',3'-Dideoxyadenosine 5'-triphosphate
立即咨询
咨询类型：
*姓名：
*电话：
*单位：
Email：
*留言内容：
请详细说明您的需求。
*验证码：
2',3'-Dideoxyadenosine 5'-triphosphate
本半岛bd体育手机客户端 不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
2',3'-Dideoxyadenosine 5'-triphosphate图片
CAS NO: 24027-80-3
包装: 100μL
市场价: 1610元

半岛bd体育手机客户端 介绍
2',3'-Dideoxyadenosine 5'-triphosphate (2',3'-Dideoxyadenosine 5'-triphosphate), an active metabolite of 2',3'-dideoxyinosine, is a chain-elongating inhibitor of DNA polymerase.
Cas No. 24027-80-3
别名 2',3'-Dideoxyadenosine 5'-triphosphate
Canonical SMILES O=P(OP(OP(O)(O)=O)(O)=O)(O)OC[C@@H]1CC[C@H](N2C=NC3=C2N=CN=C3N)O1
分子式 C10H16N5O11P3
分子量 475.2
溶解度 Water: soluble
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

2',3'-Dideoxyadenosine 5'-triphosphate (ddATP) is an in vitro inhibitor of reverse transcriptases from retroviruses, including HIV-1 and visna (Kis = 20 and 37 nM, respectively). It also blocks, in vitro, mammalian and bacterial DNA polymerases. ddATP, produced intracellularly by the phosphorylation of exogenously supplied 2',3'-dideoxyadenosine, competes with dATP, resulting in chain termination. Because of this activity, dideoxynucleoside 5'-triphosphates, including ddATP, are used to terminate chain extension produced by the Taq polymerase used in polymerase chain reactions. It is also an antagonist of the purinergic receptor P2X2/3 (pIC50 = 6.5).
Baidu
map