Pioglitazone D4 - 半岛电竞官方网址

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Pioglitazone D4

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1134163-29-3

包装与价格：

半岛bd体育手机客户端介绍

PioglitazoneD4(U72107D4)是一种Pioglitazone氘代物。Pioglitazone(U72107)是一种有效的选择性PPARγ激动剂，高亲和力结合到PPARγ配体结合域，作用于人和鼠PPARγ，EC50分别为0.93和0.99μM。

Cas No.	1134163-29-3
别名	匹格列酮-D4,U 72107-d4
Canonical SMILES	O=C(N1)SC(CC2=C([2H])C([2H])=C(OCCC3=NC=C(CC)C=C3)C([2H])=C2[2H])C1=O
分子式	C₁₉H₁₆D₄N₂O₃S
分子量	360.46
溶解度	DMF: 2.5 mg/ml,DMSO: 2.5 mg/ml
储存条件	Store at -20℃
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	Pioglitazone D4 (U 72107 D4) is a deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively[1]. [1]. Kuwabara K, et al. A novel selective peroxisome proliferator-activated receptor alpha agonist, 2-methyl-c-5-[4-[5-methyl-2-(4-methylphenyl)-4-oxazolyl]butyl]-1,3-dioxane-r-2-carboxylic acid (NS-220), potently decreases plasma triglyceride and glucose leve