| CAS NO: | 357336-74-4 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| Cas No. | 357336-74-4 |
| 别名 | Ucb 44212 |
| 分子式 | C10H14F2N2O2 |
| 分子量 | 232.23 |
| 储存条件 | Store at -20°C, stored under nitrogen |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 | Seletracetam (Ucb 44212), as an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy[1][2][3]. Seletracetam decreases seizure activity in a number of epilepsy models and binds to the synaptic vesicle protein SV2A[2].Seletracetam decreases synaptic responses in a time-, frequency- and concentration-dependent manner[2].Seletracetam modifies rates of presynaptic release[2].Seletracetam inhibits high-voltage-activated Ca2+ currents and intracellular Ca2+ increase in rat cortical neurons in vitro[3]. [1]. Pollard JR, et al. Seletracetam, a small molecule SV2A modulator for the treatment of epilepsy. Curr Opin Investig Drugs. 2008 Jan;9(1):101-7. |
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