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Alkyne-ethyl-PEG1-Boc
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Alkyne-ethyl-PEG1-Boc图片
CAS NO: 2100306-55-4
包装: 1g
市场价: 7428元

半岛bd体育手机客户端 介绍
Alkyne-ethyl-PEG1-Boc 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。
Cas No. 2100306-55-4
别名 Alkyne-ethyl-PEG1-t-butyl ester
分子式 C11H18O3
分子量 198.26
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

Alkyne-ethyl-PEG1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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