Mal-PEG5-NHS ester 是一种基于 PEG 和 Alkyl/ether 的 PROTAC linker，可用于 PROTAC 的合成。
| Cas No. |
1807537-42-3 |
| 分子式 |
C21H30N2O11 |
| 分子量 |
486.47 |
| 储存条件 |
Store at -20°C |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 |
Mal-PEG5-NHS ester is an Alkyl/ether and PEG-basedPROTAC linkercan be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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