PROTACBETDegrader-3是基于PROTAC技术的BET降解剂。
Canonical SMILES |
CCN1N=C(C2CC2)C=C1NC3=NC(C(NCCOCCOCC(N[C@@H](C(C)(C)C)C(N4[C@H](C(NCC5=CC=C(C6=C(C)N=CS6)C=C5)=O)C[C@@H](O)C4)=O)=O)=O)=NC7=C3C8=CC(OC)=C(C(C(C)=NO9)=C9C)C=C8N7 |
分子式 |
C53H64N12O9S |
分子量 |
1045.22 |
溶解度 |
DMSO : 100 mg/mL (95.67 mM);Water :< 0.1 mg/mL (insoluble) |
储存条件 |
Store at -20°C |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
半岛bd体育手机客户端 描述 |
PROTAC BET Degrader-3 is a potent BET degrader based on PROTAC. |