Cyclic di-GMP sodium (c-di-GMP sodium) 是一种 STING 激活剂和无处不在的第二信使,调节生物膜的形成、运动和各种细菌的毒力。
别名 |
c-di-GMP sodium; cyclic diguanylate sodium; 5GP-5GP sodium |
分子式 |
C20H24N10O14P2.xNa |
储存条件 |
Store at -20°C |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
半岛bd体育手机客户端 描述 |
Cyclic di-GMP sodium (c-di-GMP sodium) is a STING activator and a global bacterial second messenger, which regulates biofilm formation, motility, and virulence in diverse bacterial species[1][2]. [1]. Wang Z, et al. STING activator c-di-GMP enhances the anti-tumor effects of peptide vaccines in melanoma-bearing mice. Cancer Immunol Immunother. 2015;64(8):1057-1066. [2]. Burdette DL, Monroe KM, Sotelo-Troha K, et al. STING is a direct innate immune sensor of cyclic di-GMP. Nature. 2011;478(7370):515-518. Published 2011 Sep 25. |