Hydroflumethiazide (Methforylthiazidine) 是一种口服有效的噻嗪类利尿剂。
| Cas No. |
135-09-1 |
| 别名 |
氢氟噻嗪,Methforylthiazidine; Rontyl |
| Canonical SMILES |
O=S1(C2=C(C=C(C(F)(F)F)C(S(N)(=O)=O)=C2)NCN1)=O |
| 分子式 |
C8H8F3N3O4S2 |
| 分子量 |
331.3 |
| 溶解度 |
DMSO: Slightly Soluble,Methanol: Slightly Soluble |
| 储存条件 |
Store at -20°C |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 |
Hydroflumethiazide is a thiazide diuretic that also inhibits carbonic anhydrase (CA). It is selective for CAII, VB, VII, IX, XII, and XIV (Kis = 305-235 nM) over CAI, IV, and VI (Kis = 2,840-8,250 nM) and CAIII, VA, and XIII (Kis = >10 ?M). Diuretics of the thiazide class, of which hydroflumethiazide is a member, inhibit the renal Na+/Cl- cotransporter. Formulations containing hydroflumethiazide have been used as diuretics. |
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