DBCO-Sulfo-NHS ester sodium 是一种可降解 (cleavable) 的 ADC linker,用于抗体偶联药物 (ADCs) 的合成。
Cas No. |
1400191-52-7 |
分子式 |
C25H21N2NaO8S |
分子量 |
532.5 |
储存条件 |
Store at -20°C |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
半岛bd体育手机客户端 描述 |
DBCO-Sulfo-NHS ester sodium is a cleavableADC linkerused in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
[1]. Jung S, et al. Facile strategy for protein conjugation with chitosan-poly(ethylene glycol) hybrid microparticleplatforms via strain-promoted alkyne-azide cycloaddition (SPAAC) reaction. Biomacromolecules. 2013 Nov 11;14(11):3892-902. |