Propargyl-PEG3-phosphonic acid diethyl ester

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Propargyl-PEG3-phosphonic acid diethyl ester

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1052678-30-4

包装与价格：

半岛bd体育手机客户端介绍

Propargyl-PEG3-phosphonic acid diethyl ester 是一种 PROTAC linker，属于 PEG 类。Propargyl-PEG3-phosphonic acid diethyl ester 可用于合成一系列 PROTAC 分子。

Cas No.	1052678-30-4
分子式	C₁₃H₂₅O₆P
分子量	308.31
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	Propargyl-PEG3-phosphonic acid diethyl ester is a PEG-basedPROTAC linkercan be used in the synthesis of PROTACs^[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. [1]. Thorsten Heidelberg, et al. Oligo-ethylene glycol based phosphonate surface modification reagents and use thereof. WO2015065168A1