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Quassin
本半岛bd体育手机客户端 不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Quassin图片
CAS NO: 76-78-8
包装与价格：
包装 价格(元)
1mg 电议
5mg 电议
10mg 电议

半岛bd体育手机客户端 介绍
Quassin (Nigakilactone D) 是一种来自 Quassia amara 茎皮提取物的生物活性三萜类化合物。
Cas No. 76-78-8
别名 苦木素,Nigakilactone D
Canonical SMILES C[C@]12[C@@]3([H])[C@@]4([C@@]([C@@H](C=C(C4=O)OC)C)([H])C[C@@]1([H])OC(C[C@@]2([H])C(C)=C(C3=O)OC)=O)C
分子式 C22H28O6
分子量 388.5
溶解度 DMSO: soluble
储存条件 -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

Quassin is a quassinoid that has been found inQ. amaraand has diverse biological activities.1,2,3It is active against chloroquine-sensitive and -resistant strains ofP. falciparum(IC50= 0.15 ?M for both).1Quassin has antifeedant and insecticidal activity against the diamondback moth (P. xylostella) when applied to dietary cabbage leaf discs at 16, 31.9, or 63.7 ?g/cm2.2It increases viability of SH-SY5Y cells in a model of hydrogen peroxide-induced neuronal injury when used at concentrations of 25, 50, or 100 ?M.3

1.Mishra, K., Chakraborty, D., Pal, A., et al.Plasmodium falciparum: in vitro interaction of quassin and neo-quassin with artesunate, a hemisuccinate derivative of artemisininExp. Parasitol.124(4)421-427(2010) 2.Daido, M., Fukamiya, N., Okano, M., et al.Antifeedant and insecticidal activity of quassinoids against diamondback moth (Plutella xylostella)Biosci. Biotechnol. Biochem.57(2)2440246(1993) 3.He, C., Wang, Y., Yang, T., et al.Quassinoids with insecticidal activity against Diaphorina citri Kuwayama and neuroprotective activities from Picrasma quassioidesJ. Agric. Food. Chem.68(1)117-127(2020)
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