ORL1antagonist1是阿片样受体1(ORL1)拮抗剂,IC50值为61nM。
Cas No. |
1174985-59-1 |
Canonical SMILES |
CC1=C(C2=CC=CN=C2)N(C3=NC=CC=C3Cl)N=C1CNC4CCCC4 |
分子式 |
C20H22ClN5 |
分子量 |
367.88 |
溶解度 |
Soluble in DMSO |
储存条件 |
Store at -20°C |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
半岛bd体育手机客户端 描述 |
ORL1 antagonist 1 is an opioid receptor-like 1 (ORL1) antagonist with an IC50 of 61 nM. ORL1 antagonist 1 is compound 17[1]. [1]. Kobayashi K, et al. Discovery of novel arylpyrazole series as potent and selective opioid receptor-like 1 (ORL1) antagonists. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3627-31. |