[Met5]-Enkephalin,amide(5-Methionine-enkephalin amide)

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[Met5]-Enkephalin,amide(5-Methionine-enkephalin amide)

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

60117-17-1

包装与价格：

半岛bd体育手机客户端介绍

[Met5]-Enkephalin, amide (5-Methionine-enkephalin amide) 是 δ 的激动剂；阿片受体以及推定的 &zeta； (zeta) 阿片受体。

Cas No.	60117-17-1
别名	甲硫氨酸脑啡肽酰胺,5-Methionine-enkephalin amide
Canonical SMILES	Tyr-Gly-Gly-Phe-Met-NH2
分子式	C₂₇H₃₆N₆O₆S
分子量	572.68
溶解度	Soluble in DMSO
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	[Met5]-Enkephalin, amide is an agonist for δ opioid receptors as well as putative ζ (zeta) opioid receptors. [Met5]-Enkephalin at 0.1 nM, 10 nM, and 1 μM significantly reduces the total number of glial cells in culture[1]. [Met5]-Enkephalin, amide acts via δ-opioid receptor to inhibit pelvic nerve-evoked contractions of cat distal colon. [Met5]-enkephalin causes concentration-dependent, reversible inhibition of pelvic nerve-evoked contractions, with an IC50 value of 2.2 nM. [Met5]enkephalin at a concentration (3 nM) which produces a large inhibition of neurogenic contractions, has no effect on contractions to exogenous acetylcholine[2]. [1]. Stiene-Martin A, et al. Glial growth is regulated by agonists selective for multiple opioid receptor types in vitro. J Neurosci Res. 1991 Aug;29(4):538-48. [2]. Kennedy C, et al. [Met5]enkephalin acts via delta-opioid receptors to inhibit pelvic nerve-evoked contractions of cat distal colon. Br J Pharmacol. 1987 Oct;92(2):291-8.