生物活性

Mirin可防止ATM激活以响应双链断裂（IC50 = 12 uM），并诱导G2细胞周期停滞。

靶点信息

MRN

化学数据

目录号	A15842
作用机制	Inhibitor (抑制剂)
M. Wt	220.25
Formula	C10H8N2O2S
Purity	>99%
Storage	Store lyophilized at -20?C, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1198097-97-0
SMILES	O=C1NC(S/C1=C\C2=CC=C(O)C=C2)=N

溶解度

In vitro	DMSO	42 mg/mL (190.69 mM)
	Water	Insoluble
	Ethanol	Insoluble
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	45.4 mL	227.01 mL	454.03 mL
0.5 mM	9.08 mL	45.4 mL	90.81 mL
1 mM	4.54 mL	22.7 mL	45.4 mL
5 mM	0.91 mL	4.54 mL	9.08 mL

*The above data is based on the productmolecular weight 220.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.