5-hydroxy-Nω-methyl Tryptamine is a metabolite of serotonin in humans that has also been found in plants.
Cas No. |
15558-50-6 |
别名 |
5-羟基-N-甲基色胺草酸盐 |
Canonical SMILES |
CN([H])CCC1=CNC2=CC=C(O)C=C21.OC(C(O)=O)=O |
分子式 |
C11H14N2O?XC2H2O4 |
分子量 |
280.3 |
溶解度 |
DMF: 3 mg/mL,DMSO: 3 mg/mL,PBS (pH 7.2): 2.5 mg/mL |
储存条件 |
Store at -20°C |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
半岛bd体育手机客户端 描述 |
5-hydroxy-Nω-methyl Tryptamine is a metabolite of serotonin in humans that has also been found in plants. It is an agonist of the 5-HT receptor subtype 5-HT7 (IC50 = 23 pM in a radioligand binding assay). 5-hydroxy-Nω-methyl Tryptamine increases intracellular cyclic AMP production in HEK293 cells expressing 5-HT7 (EC50 = 22 nM). It inhibits serotonin uptake in HEK293 cells expressing human serotonin transporters (IC50 = 490 nM). Elevated levels of urinary 5-hydroxy-Nω-methyl tryptamine have been found in patients with schizophrenia, depression, and epilepsy. |