Dolastatin 15 (DLS 15) 是一种源自 Dolabella auricularia 的缩肽，是一种有效的抗有丝分裂剂，在结构上与抗微管蛋白剂 Dolastatin 10 相关。Dolastatin 15 在多发性骨髓瘤细胞中诱导细胞周期停滞和细胞凋亡。 Dolastatin 15 可用作 ADC 细胞毒素。
| Cas No. |
123884-00-4 |
| 别名 |
DLS 15 |
| 分子式 |
C45H68N6O9 |
| 分子量 |
837.07 |
| 溶解度 |
Methanol: soluble |
| 储存条件 |
Store at -20°C |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 |
Dolastatin 15 originally isolated from the sea hare Dolabella auricularia belongs to a family of antimitotic and antineoplastic depsipeptides inducing apoptosis in various malignant cell types. It was shown to inhibit the growth of the P388 lymphocytic |
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