| Cas No. |
626604-39-5 |
| 别名 |
GSK-3BETA抑制剂XI |
| 化学名 |
3-[1-(3-hydroxypropyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-4-(2-pyrazinyl)-1H-pyrrole-2,5-dione |
| Canonical SMILES |
O=C(N1)C(C2=CN=CC=N2)=C(C3=CN(CCCO)C4=C3C=CC=N4)C1=O |
| 分子式 |
C18H15N5O3 |
| 分子量 |
349.3 |
| 溶解度 |
DMSO: 5 mg/ml |
| 储存条件 |
Store at -20°C |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 |
GSK3β inhibitor XI is a potent inhibitor of glycogen synthase kinase 3β (GSK3β; Ki = 25 nM). It is selective for GSK3β over a panel of 79 kinases at a concentration of 10 μM. GSK3β inhibitor XI inhibits GSK3β in HEK293 cells (EC50 = 32 nM). |
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