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UDP-α-D-Galactose(sodium salt)
本半岛bd体育手机客户端 不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
UDP-α-D-Galactose(sodium salt)图片
CAS NO: 137868-52-1
包装与价格：
包装 价格(元)
5mg 电议
10mg 电议
25mg 电议
50mg 电议

半岛bd体育手机客户端 介绍
A nucleotide sugar
Cas No. 137868-52-1
别名 UDP-Α-D半乳糖二钠盐
Canonical SMILES O[C@H]1[C@@](N2C(NC(C=C2)=O)=O)([H])O[C@@H]([C@H]1O)COP(OP(O[C@H]3O[C@@H]([C@@H]([C@@H]([C@H]3O)O)O)CO)([O-])=O)([O-])=O.[Na+].[Na+]
分子式 C15H23N2Na2O17P2
分子量 611.27
溶解度 PBS (pH 7.2): 10 mg/ml
储存条件 -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

UDP-α-D-galactose is an endogenous nucleotide sugar that is used by glycosyltransferases to transfer α-D-galactose residues to substrates.1It is an agonist of the purinergic P2Y14receptor (EC50= 0.67 ?M), an atypical P2Y receptor involved in the activation of dendritic and glial cells.2Levels of UDP-α-D-galactose in red blood cells are decreased in patients with phenylketonuria (PKU) and maple syrup urine disease, inborn errors of amino acid metabolism characterized by mutations in the gene encoding phenylalanine hydroxylase (PAH) and a deficiency in the branched-chain α-keto acid dehydrogenase enzyme complex, respectively.3

1.Hennet, T.The galactosyltransferase familyCell Mol. Life Sci.59(7)1081-1095(2002) 2.Jacobson, K.A., Ivanov, A.A., de Castro, S., et al.Development of selective agonists and antagonists of P2Y receptorsPurinergic Signal.5(1)75-89(2009) 3.Gibson, J.B., Berry, G.T., Palmieri, M.J., et al.Sugar nucleotide concentrations in red blood cells of patients on protein- and lactose-limited diets: Effect of galactose supplementationAm. J. Clin. Nutr.63(5)704-708(1996)
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