19-Hydroxybufalin是一种蟾二烯羟酸内酯,可抑制上皮间质转化,减弱PC3细胞的迁移和侵袭。
Cas No. |
39844-86-5 |
别名 |
19-羟基蟾毒灵 |
Canonical SMILES |
O=C(C=C1)OC=C1[C@H]2CC[C@]3(O)[C@]4([H])CC[C@]5([H])C[C@@H](O)CC[C@]5(CO)[C@@]4([H])CC[C@]23C |
分子式 |
C24H34O5 |
分子量 |
402.52 |
溶解度 |
DMSO: 100 mg/mL (248.43 mM) |
储存条件 |
4°C, protect from light |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
半岛bd体育手机客户端 描述 |
19-Hydroxybufalin is a bufadienolide, inhibits epithelial-mesenchymal transition and attenuates the migration and invasion of PC3 cells[1]. [1]. Chen L, et al. Arenobufagin inhibits prostate cancer epithelial-mesenchymal transition and metastasis by down-regulating β-catenin. Pharmacol Res. 2017 Sep;123:130-142. |