| CAS NO: | 1378976-02-3 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| Cas No. | 1378976-02-3 |
| Canonical SMILES | ClC1=CC=C(O)C(C2=CN=NN2)=C1 |
| 分子式 | C8H6ClN3O |
| 分子量 | 195.6 |
| 溶解度 | DMF: 20mg/mL,DMF:PBS (pH 7.2) (1:4): 0.2mg/mL,DMSO: 15mg/mL,Ethanol: 15mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 | MMG-0358 is an inhibitor of indolamine 2,3-dioxygenase 1 (IDO1; IC50s = 2 and 80 nM for the mouse and human enzyme, respectively).1,2It is selective for IDO1 over tryptophan 2,3-dioxygenase (TDO; IC50s = >100 ?M for mouse and human TDO).1 1.R?hrig, U.F., Majjigapu, S.R., Grosdidier, A., et al.Rational design of 4-aryl-1,2,3-triazoles for indoleamine 2,3-dioxygenase 1 inhibitionJ. Med. Chem.55(11)5270-5290(2012) 2.R?hrig, U.F., Reynaud, A., Majjigapu, S.R., et al.Inhibition mechanisms of indoleamine 2,3-dioxygenase 1 (IDO1)J. Med. Chem.62(19)8784-8795(2019) |
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