| CAS NO: | 5294-61-1 |
| 包装 | 价格(元) |
| 250mg | 电议 |
| 500mg | 电议 |
| 1 g | 电议 |
| 5 g | 电议 |
| Cas No. | 5294-61-1 |
| 别名 | N-(2,6-二甲基苯基)-1-哌嗪乙酰胺 |
| Canonical SMILES | O=C(CN1CCNCC1)NC2=C(C)C=CC=C2C |
| 分子式 | C14H21N3O |
| 分子量 | 247.3 |
| 溶解度 | DMF: 10 mg/ml,DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml,DMSO: 5 mg/ml,Ethanol: 5 mg/ml |
| 储存条件 | -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 | CVT-2738 is an active metabolite of the antianginal agent ranolazine .1It is formed from ranolazine by the cytochrome P450 (CYP) isoform CYP3A. CVT-2738 (100 mg/kg) inhibits increases in T-wave height and the RR interval in a mouse model of myocardial ischemia induced by isoprenaline .2 1.Wang, Y., Chen, X., Sun, Z., et al.Development and validation of a sensitive LC-MS/MS assay for simultaneous quantitation of ranolazine and its three metabolites in human plasmaJ. Chromatogr. B889-89010-16(2012) 2.Yao, Z., Gong, S., Guan, T., et al.Synthesis of ranolazine metabolites and their anti-myocardial ischemia activitiesChem. Pharm. Bull. (Tokyo)57(11)1218-1222(2009) |
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