Naloxone methiodide - 半岛电竞官方网址

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Naloxone methiodide

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

半岛bd体育手机客户端介绍

Naloxone methiodide 是一种外周限制性、非选择性和竞争性阿片受体 (opioid receptor) 拮抗剂。Naloxone methiodide 不能穿透血脑屏障。

Cas No.	93302-47-7
分子式	C₂₀H₂₄INO₄
分子量	469.31
溶解度	DMSO : 250 mg/mL (532.70 mM; Need ultrasonic)
储存条件	4°C, away from moisture
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	Naloxone methiodide is a peripherally restricted, nonselective, and competitive opioid receptor antagonist. Naloxone methiodide does not penetrate the blood-brain barrier[1][2]. Naloxone‐methiodide (10 mg/mL; 200 μL; i.p.), induces abdominal hypersensitivity in IL-10-/- mice with colitis[2]. [1]. Basso L, et al. TRPV1 promotes opioid analgesia during inflammation. Sci Signal. 2019;12(575):eaav0711. Published 2019 Apr 2. [2]. Basso L, et al. Endogenous control of inflammatory visceral pain by T cell-derived opioids in IL-10-deficient mice. Neurogastroenterol Motil. 2020;32(2):e13743.