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Miro1 Reducer
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Miro1 Reducer图片
包装与价格:
包装 价格(元)
10mg 电议
50mg 电议

半岛bd体育手机客户端 介绍
Canonical SMILES FC1=CC=CC(NC(NC2=CC=C(C=C2)NC3=CC(N4C=CN=C4)=NC=N3)=O)=C1.Cl
分子式 C20H16FN7O.HCl
分子量 425.85
溶解度 DMSO|42.58|100|
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

Promotes proteasomal degradation of Miro1 (mitochondrial Rho GTPase 1). Reduces Miro1 levels in fibroblasts from Parkinson's disease (PD) patients (IC50 = 7.8 μM). Exhibits no significant effect on related outer mitochondrial membrane protein Mitofusin. Reduces stress-induced degeneration of dopaminergic neurons derived from PD patient iPSCs. Rescues age-dependent neuronal loss and prolongs lifespan in fly PD models.

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