MoTP 是一种特异性血小板活化因子受体拮抗剂,可诱导黑色素细胞消融。 MoTP可用于癌症的研究。
Cas No. |
57055-82-0 |
Canonical SMILES |
OC1=CC=C(SCCCCN2CCOCC2)C=C1 |
分子式 |
C14H21NO2S |
分子量 |
267.4 |
溶解度 |
DMF: 33 mg/ml,DMSO: 25 mg/ml,Ethanol: 0.3 mg/ml,PBS (pH 7.2): 5 mg/ml |
储存条件 |
Store at -20°C |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
半岛bd体育手机客户端 描述 |
MoTP, known more formally as 4-(4-morpholinobutylthio)phenol, is used to ablate larval melanocytes in zebrafish in order to study melanocyte regeneration. MoTP is converted to a cytotoxin in cells with high tyrosinase activity, which in the zebrafish embryo are limited to melanoblasts and newly formed melanocytes. The wash-out of MoTP allows regeneration through the proliferation of melanocyte stem cells. |