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ONO-9780307
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ONO-9780307图片
CAS NO: 856691-44-6
包装与价格:
包装 价格(元)
5mg 电议
10mg 电议

半岛bd体育手机客户端 介绍
ONO-9780307 是一种特异性的 LPA1 (lysophosphatidic acid receptor 1) 拮抗剂,其IC50 的值为 2.7 nM。
Cas No. 856691-44-6
分子式 C30H35NO7
分子量 521.6
溶解度 DMSO : 190 mg/mL (364.26 mM; Need ultrasonic)
储存条件 4°C, protect from light
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

ONO-9780307 is a specific synthetic LPA1 (lysophosphatidic acid receptor 1) antagonist with an IC50 value of 2.7 nM[1].

VT107 (0.1~10000 μM; LPA1-B103 and Vector-B103 cells) results in inhibition of Ca2+ mobilization[1].ONO-9780307 is used to solve the LPA1 crystal structure, binds to an orthosteric site in LPA1[1].

[1]. Mizuno H, et al. Lysophospholipid G protein-coupled receptor binding parameters as determined by backscattering interferometry. J Lipid Res. 2019;60(1):212-217.

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