您好,欢迎来到半岛电竞官方网址 ! [ 登录] [ 免费注册]
半岛电竞官方网址
位置: 首页> 半岛bd体育手机客户端 库> BOP
立即咨询
咨询类型:
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
BOP
本半岛bd体育手机客户端 不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BOP图片
CAS NO: 1947348-42-6
包装与价格:
包装 价格(元)
10mg 电议
50mg 电议

半岛bd体育手机客户端 介绍
BOP 是一种有效和选择性的双重 α9β1/α4β1 整合素抑制剂,Kd 值在皮摩尔范围内。
Cas No. 1947348-42-6
Canonical SMILES O=C([C@@H](NC([C@@H]1CCCN1S(=O)(C2=CC=CC=C2)=O)=O)CC3=CC=C(C=C3)OC(N4CCCC4)=O)O[Na]
分子式 C25H28N3O7SNa
分子量 537.56
溶解度 Soluble in DMSO
储存条件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

Dual α9β1/α4β1 integrin inhibitor; rapidly and preferentially mobilizes HSCs and progenitors. Augments HSC mobilization in combination with AMD3100 . High affinity fluorescent derivative R-BC154 also available.

Cao et al (2014) Design, synthesis and binding properties of a fluorescent α9β1/α4β1 integrin antagonist and its application as an in vi Org.Biomol.Chem. 12 965 PMID:24363056 |Pepinsky et al (2002) Comparative assessment of the ligand and metal ion binding properties of integrins α9β1 and α4β1. Biochemistry 41 7125 PMID:12033947 |Cao et al (2016) Therapeutic targeting and rapid mobilization of endosteal HSC using a small molecule integrin antagonist. Nat.Commun. 7 11007 PMID:26975966

Baidu
map