Bryostatin 3 是一种大环内酯,是一种蛋白激酶 C 激活剂,Ki 为 2.75 nM。 Bryostatin 3 可以阻断 12-O-tetradecanoylphorbol-13-acetate (TPA) 对细胞增殖的抑制作用,但不能阻断 TPA 增强的细胞-基质粘附。
Cas No. |
143370-84-7 |
Canonical SMILES |
CC([C@@]1(O)[C@@H](OC(/C=C/C=C/CCC)=O)C([C@H]2[C@@H]3O1)=CC(O2)=O)(C)/C=C/[C@H](O[C@H](C[C@]4(O)O[C@H](C[C@@H](O)CC(O[C@@H]([C@H](O)C)C3)=O)C[C@H](OC(C)=O)C4(C)C)C/5)CC5=C/C(OC)=O |
分子式 |
C46H64O17 |
分子量 |
888.99 |
溶解度 |
Soluble in ethanol |
储存条件 |
Store at -20℃ |
General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition |
Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |