Tephrosin(synthetic) - 半岛电竞官方网址

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Tephrosin(synthetic)

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

76-80-2

包装与价格：

半岛bd体育手机客户端介绍

Tephrosin (synthetic) 是一种天然类鱼素，具有强大的抗肿瘤活性。 Tephrosin（合成的）通过诱导受体的内化来诱导 EGFR 和 ErbB2 的降解。

Cas No.	76-80-2
别名	灰叶草素; Deguelinol I; Hydroxydeguelin
Canonical SMILES	CC(C=C1)(C)OC2=C1C(O3)=C(C=C2)C([C@@]([C@@]3([H])CO4)(O)C5=C4C=C(OC)C(OC)=C5)=O
分子式	C₂₃H₂₂O₇
分子量	410.4
溶解度	Chloroform: soluble
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	Tephrosin is a rotenoid first isolated from the leaves and seeds of T. purpurea and T. vogelii that exhibits antineoplastic and piscicidal activities. The toxic actions of this compound are attributed to its ability to inhibit the NADH:ubiquinone oxidoreductase with an IC50 value of 98nM. Tephrosin is also reported to induce ornithine decarboxylase activity with an IC50 value of 147 nM. Tephrosin has been shown to enhance the cytotoxic activity of 2-deoxy-D-glucose against various cancer human cancer cell lines, depleting intracellular ATP and inducing apoptosis.