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Safflower Red
本半岛bd体育手机客户端 不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Safflower Red图片
CAS NO: 36338-96-2
包装与价格：
包装 价格(元)
5 g 电议
10 g 电议
25 g 电议
50 g 电议

半岛bd体育手机客户端 介绍
A red pigment with diverse biological activities
Cas No. 36338-96-2
别名 红花黄色素
Canonical SMILES O[C@](C(O)=C1C(/C=C/C(C=C2)=CC=C2O)=O)([C@]([C@@H]([C@H]3O)O)([H])O[C@@H]([C@H]3O)CO)C(/C(C1=O)=C\C(C(C(C(/C=C/C(C=C4)=CC=C4O)=O)=C5O)=O)=C([C@]5([C@]([C@@H]([C@H]6O)O)([H])O[C@@H]([C@H]6O)CO)O)O)=O
分子式 C43H42O22
分子量 910.8
溶解度 DMF: 1 mg/ml,DMSO: 5 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件 -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

Safflower red is a polyketide synthase-derived quinochalcone glucoside red pigment originally isolated fromC. tinctoriusthat has diverse biological activities.1,2,3,4Safflower red (100 and 200 ?M) inhibits LPS-induced decreases in collagen II and aggrecan levels and reverses LPS-induced increases inTNFexpression in isolated rat nucleus pulposus cells.3It reverses decreases in serum glutathione (GSH) and superoxide dismutase (SOD) levels and increases in serum malondialdehyde (MDA) levels, as well as decreases infarct area and brain edema induced by middle cerebral artery occlusion (MCAO), in a rat model of cerebral ischemia-reperfusion injury when administered at a dose of 40 mg/kg.4Formulations containing safflower red have been used in the food, cosmetics, and clothing industries.

1.Shinozaki, J., Kenmoku, H., Nihei, K., et al.Cloning and functional analysis of three chalcone synthases from the flowers of safflowers Carthamus tinctoriusNat. Prod. Commun.11(6)787-790(2016) 2.Kazuma, K., Takahashi, T., Sato, K., et al.Quinochalcones and flavonoids from fresh florets in different cultivars of Carthamus tinctorius LBiosci. Biotechnol. Biochem.64(8)1588-1599(2000) 3.Chen, B., Wang, H.-T., Yu, B., et al.Carthamin yellow inhibits matrix degradation and inflammation induced by LPS in the intervertebral disc via suppression of MAPK pathway activationExp. Ther. Med.14(2)1614-1620(2017) 4.Guo, H., Zhu, L., Tang, P., et al.Carthamin yellow improves cerebral ischemia?reperfusion injury by attenuating inflammation and ferroptosis in ratsInt. J. Mol. Med.47(4)52(2021)
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