Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne - 半岛电竞官方网址

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Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne

本半岛bd体育手机客户端不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2241685-22-1

包装与价格：

半岛bd体育手机客户端介绍

Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Cas No.	2241685-22-1
分子式	C₄₂H₆₂N₄O₉SSi
分子量	827.11
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端描述	Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1]. [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562