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Angiotensin 1/2(2-7)
本半岛bd体育手机客户端 不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Angiotensin 1/2(2-7)图片
包装与价格：
包装 价格(元)
5mg 电议
10mg 电议
25mg 电议

半岛bd体育手机客户端 介绍

Vasoconstrictor

别名 H2N-Arg-Val-Tyr-Ile-His-Pro-OH
Canonical SMILES N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@@H]([C@H](C)CC)C(N[C@@H](CC2=CNC=N2)C(N3CCC[C@@H]3C(O)=O)=O)=O)=O)=O)=O
分子式 C37H57N11O8
分子量 783.92
溶解度 ≥ 78.4mg/mL in DMSO
储存条件 Store at -20℃
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
半岛bd体育手机客户端 描述

Angiotensin I/II (2-7) is a peptide (ARG-VAL-TYR-ILE-HIS-PRO) that contains the amino acids 2-7 and is converted from Angiotensin I/II peptide.

Angiotensin I is formed by the action of renin on angiotensinogen, an ?-2-globulin with 12 amino acids. Angiotensinogen is produced constitutively and released into the circulation mainly by the liver. Renin cleaves the peptide bond between the leucine (Leu) and valine (Val) residues on angiotensinogen, creating the ten-amino acid peptide angiotensin I. Angiotensin I is converted to angiotensin II (AII) through removal of two C-terminal residues by angiotensin-converting enzyme (ACE), primarily by ACE within the lung.

Angiotensin is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure. Angiotensin also stimulates the release of aldosterone, which promotes sodium retention in the distal nephron, thereby increasing blood pressure.

References:
1. Basso N, Terragno NA (December 2001). "History about the discovery of the renin-angiotensin system". Hypertension 38 (6): 1246-9.
2. Richard A. Preston. et. (1998). pAge-Race Subgroup Compared With Renin Profile as Predictors of Blood Pressure Response to Antihypertensive Therapyq. JAMA. 1998;280(13):1168-1172.
3. Williams GH, Dluhy RG (2008). "Chapter 336: Disorders of the Adrenal Cortex". In Loscalzo J, Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL. Harrison's principles of internal medicine. McGraw-Hill Medical.
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