Policresulen 是一种有效的 DENV2 NS2B/NS3 蛋白酶抑制剂 (IC50 为 0.48 μg/mL)。Policresulen 抑制 BHK-21 细胞中的 DENV2 复制，IC50 为 4.99 μg/mL。Policresulen 作为蛋白酶的竞争性抑制剂，对蛋白酶的稳定性有轻微影响。
| Cas No. |
101418-00-2 |
| 分子式 |
(C8H10O4S)n |
| 储存条件 |
4°C, away from moisture and light |
| General tips |
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition |
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 半岛bd体育手机客户端 描述 |
Policresulen is a potent inhibitor ofDENV2 NS2B/NS3 protease(IC50of 0.48 μg/mL). Policresulen inhibits DENV2 replication in BHK-21 cells with IC50of 4.99 μg/mL. Policresulen acts as a competitive inhibitor of the protease, and slightly affects the protease stability[1]. |
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