生物活性
PJ34是新型有效的PARP-1/2特异性抑制剂，EC50为20 nM。
化学数据
| 目录号 |
A15215 |
| 作用机制 |
Inhibitor (抑制剂) |
| M. Wt |
295.34 |
| Formula |
C17H17N3O2 |
| Purity |
>99% |
| Storage |
Store lyophilized at -20?C, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
| CAS No. |
344458-19-1 |
| Synonyms |
PJ-34, PJ 34 |
| SMILES |
CN(C)CC(=O)NC1=CC2=C(C=C1)NC(=O)C3=CC=CC=C32 |
储备液配制
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 0.1 mM |
33.86 mL |
169.3 mL |
338.59 mL |
| 0.5 mM |
6.77 mL |
33.86 mL |
67.72 mL |
| 1 mM |
3.39 mL |
16.93 mL |
33.86 mL |
| 5 mM |
0.68 mL |
3.39 mL |
6.77 mL |
*The above data is based on the productmolecular weight 295.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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