生物活性
Voglibose是缬氨酰胺的N取代衍生物,对α-葡萄糖苷酶具有出色的抑制活性,并且对高血糖症和由高血糖症引起的各种疾病具有抗药性。
靶点信息
化学数据
目录号 |
A14945 |
作用机制 |
Inhibitor (抑制剂) |
M. Wt |
267.13 |
Formula |
C10H21NO7 |
Purity |
>99% |
Storage |
Store lyophilized at -20?C, keep desiccated. In lyophilized form, the chemical is stable for36 months. In solution, store at -20?C and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles. |
CAS No. |
83480-29-9 |
SMILES |
C1C(C(C(C(C1(CO)O)O)O)O)NC(CO)CO |
溶解度
In vitro |
DMSO |
68 mg/mL (254.41 mM) |
Water |
68 mg/mL (254.41 mM) |
Ethanol |
Insoluble |
*<1 mg/ml means slightly soluble or insoluble. *Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
储备液配制
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
0.1 mM |
37.43 mL |
187.17 mL |
374.35 mL |
0.5 mM |
7.49 mL |
37.43 mL |
74.87 mL |
1 mM |
3.74 mL |
18.72 mL |
37.43 mL |
5 mM |
0.75 mL |
3.74 mL |
7.49 mL |
*The above data is based on the productmolecular weight 267.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.