Encainide Hydrochloride is a class Ic antiarrhythmic agent. It is no longer used because of its frequent proarrhythmic side effects. One of the anti-arrhythmia, it blocks voltage-gated sodium channels and slows conduction within the His-Purkinje system and myocardium. Encainide is a non-chiral antiarrhythmic and benzanilide analogue. References: Chase SL, Sloskey GE. Encainide hydrochloride and flecainide acetate: two class 1c antiarrhythmic agents. Clin Pharm. 1987 Nov;6(11):839-50. Review. Erratum in: Clin Pharm 1988 Apr;7(4):269. PubMed PMID: 3119276.
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CAS:66794-74-9