Gacyclidine, formerly known as OTO-311 and GK-11, is a N-methyl-D-aspartate (NMDA) receptor antagonist potentially for the treatment of tinnitus. Local administration of gacyclidine to the cochlea can suppress salicylate-induced tinnitus. Tritiated gacyclidine and its enantiomers bind to NMDA receptors with binding parameters similar to those of other non-competitive NMDA receptor antagonists. References: Chenoweth JA, Gerona RR, Ford JB, Sutter ME, Rose JS, Albertson TE, Clarke SO, Owen KP. Altered mental status and end organ damage associated with the use of gacyclidine: a case series. J Med Toxicol. 2015 Mar;11(1):115-20. doi: 10.1007/s13181-014-0415-2. PubMed PMID: 25048606; PubMed Central PMCID: PMC4371039.

纯度：≥98%

CAS：68134-81-6