基因名：
PDHA1
半岛bd体育手机客户端 别名：
E1alpha； PDHA； PDHAD； PDHCE1A； PHE1A； PDHA1； pyruvate dehydrogenase E1 subunit alpha 1； pyruvate dehydrogenase E1 subunit alpha 1； pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial； PDHE1-A type I； pyruvate dehydrogenase (lipoamide) alpha 1； pyruvate dehydrogenase E1 alpha 1 subunit； pyruvate dehydrogenase alpha 1； pyruvate dehydrogenase complex, E1-alpha polypeptide 1； 丙酮酸脱氢酶α(PDHA1)； 丙酮酸脱氢酶α1； 磷酸化丙酮酸脱氢酶α1；
背景信息：
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
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