KH-CB19 is a potent and selective inhibitor of CDC2-like kinase (CLK) 1 and 4. KH-CB19 suppresses serine/arginine-rich protein phosphorylation by CLKs under proinflammatory conditions. References: Jain P, Karthikeyan C, Moorthy NS, Waiker DK, Jain AK, Trivedi P. Human CDC2-like kinase 1 (CLK1): a novel target for Alzheimer's disease. Curr Drug Targets. 2014 May;15(5):539-50. Review. PubMed PMID: 24568585.
纯度:≥98%
CAS:1354037-26-5